CME Web Sites

The following is a list of Web sites that offer ongoing CME programs that may be of interest to you. Please be sure to check back often as we continue to update this list.

•	American Academy of CME, Inc.
•	American Association of Critical-Care Nurses (AACN)
•	CME on CD
•	criticalcareCME
•	Interactive Network for Continuing Education (INCE)
•	McMahon Medical Publishing
•	Medscape
•	Meniscus
•	Millennium CME Institute, Inc.
•	Pharmacy Practice News
•	Postgraduate Medicine Online
•	surgeryCME
•	University of Kentucky: Pharmacy & Medicine CE
•	WebMD

Indications
Argatroban is indicated as an anticoagulant for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia.

Argatroban is indicated as an anticoagulant in patients with or at risk for heparin-induced thrombocytopenia undergoing percutaneous coronary intervention (PCI).

Important Safety Information

As with all anticoagulants, bleeding is a serious concern. Argatroban is contraindicated in patients with overt major bleeding or those with hypersensitivity to the product or any of its components. Argatroban should be used with extreme caution in disease states or other circumstances in which there is an increased risk of hemorrhage. Overall major bleeding was reported in 5.3% of patients with HIT treated with Argatroban versus 6.7% of the historical controls. Overall major bleeding was reported in 1.8% of patients undergoing PCI treated with Argatroban versus 3.1% of the historical controls. Intracranial bleeding was not observed in the 568 patients treated with Argatroban for HIT (with or without thrombosis) or in the 91 patients who underwent PCI. The most common nonhemorrhagic side effects in HIT patients, regardless of the relationship to treatment, were dyspnea, hypotension, and fever. In patients undergoing PCI, the nonhemorrhagic side effects, regardless of the relationship to treatment, included chest pain, hypotension, and back pain. Please see full Prescribing Information for additional safety information on Argatroban.

Disclaimer

The www.argatroban.com web site contains links to third-party Web sites on the Internet. These links are provided as a service to individuals interested in more information in HIT. These sites are not part of this GlaxoSmithKline (GSK) Web site. The content and materials in these third-party Web sites are not produced or endorsed by GSK and may refer to uses of our products that are not recommended by GSK.