Patient Education Materials
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If You Have Been Diagnosed With Heparin-Induced Thrombocytopenia (ARG169) Questions and answers about heparin and HIT if you or someone you care about are considering surgery.
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If You Have Been Diagnosed With Heparin-Induced Thrombocytopenia - Spanish (ARG177) Common patient questions and answers on HIT. |
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Physician Clinical and Resource Materials
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Delayed-Onset of Heparin-Induced Thrombocytopenia and Thrombosis (ARG171) Warkentin, TE and Kelton, JG. Ann Intern Med. 2001;135:502-506. Author describes a syndrome termed delayed-onset heparin-induced thrombocytopenia, in which thrombocytopenia and thrombotic events begin 5 or more days after withdrawal of heparin.
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Argatroban Anticoagulation During Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (ARG058) Lewis et al. Catheterization and Cardiovascular Interventions57:177184 (2002). Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome associated with thrombosis. Alternative anticoagulation to heparin is needed for HIT patients during percutaneous coronary intervention (PCI). We evaluated argatroban, a direct thrombin inhibitor, for anticoagulation in this setting. |
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Argatroban Anticoagulation in Patients with Heparin-Induced Thrombocytopenia (ARG135) Lewis, et al. Arch Intern Med. 2003;163:1849-1856. HIT is an intensely prothrombotic syndrome managed by discontinuation of heparin therapy and treatment with an alternative inhibitor of thrombin. We describe our experience with argatroban, a direct thrombin inhibitor, in patients with HIT or HIT with thrombosis (HITTS).
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HIT Myths and Misconceptions (ARG218) Rice L. Arch Intern Med;164:1961-1964. A discussion of the myths and misconceptions about HIT that will cause trouble for you and your patients.
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Argatroban Dosing in Patients with Heparin-Induced Thrombocytopenia (ARG193) Verme-Gibboney CN, Hursting MJ. Ann Pharmacother 2003;37:970-5. Authors evaluated clinical experiences with argatroban dosing, particularly incremental dosage adjustments, during a clinical trial of argatroban anticoagulation in HIT. |
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Argatroban Anticoagulant Therapy in Patients With Heparin-Induced Thrombocytopenia (ARG108) Lewis et al. Circulation:103:14;1838-1843. Heparin-induced thrombocytopenia (HIT) is an immune-mediated syndrome caused by heparin with serious complications. We report a prospective, historical-controlled study evaluating the efficacy and safety of argatroban, a direct thrombin inhibitor, as anticoagulant therapy in patients with HIT or HIT with thrombosis syndrome (HITTS).
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Delayed-Onset of Heparin-Induced Thrombocytopenia (ARG172) Rice L, et al. Ann Intern Med. 2002;136:210-215. Author describes several clinical scenarios when the onset or manifestations of heparin-induced thrombocytopenia were delayed.
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Treatment of Heparin-Induced Thrombocytopenia (ARG174) Hirsh J, et al. Arch Intern Med. 2004;164:361-369. This systematic review summarizes the risk for thrombosis in HIT patients when heparin therapy is stopped; evidence of the efficacy of thrombin inhibitors in patients with HIT with and without thrombosis; evidence supporting the use of thrombin inhibitors in patients with a history of HIT who require a coronary intervention procedure; and the risk for bleeding when antithrombotic agents are used.
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Heparin-Induced Thrombocytopenia: One Case at A Time - VHS (ARG228) In this video, leading clinicians discuss heparin-induced thrombocytopenia through a series of patient case presentations in a variety of hospital settings and utilizing todays most relevant literature and treatment recommendations.
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Heparin-Induced Thrombocytopenia: One Case at A Time - DVD (ARG227) In this video, leading clinicians discuss heparin-induced thrombocytopenia through a series of patient case presentations in a variety of hospital settings and utilizing todays most relevant literature and treatment recommendations.
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| The Argatroban.com
Web site contains links to third-party Web sites on the Internet.
These links are provided as a service to individuals interested
in more information in HIT. These sites are not part of this GlaxoSmithKline
(GSK) Web site. The content and materials in these third-party Web
sites are not produced or endorsed by GSK and may refer to uses
of our products that are not recommended by GSK.
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